
Within the context of regular clinical practice, our results will provide evidence regarding the effects of exercise interventions on frailty among pre-frail older adults, a key population given their significant potential for functional, physical, and mental health improvement. Protocol was approved by the Ethics Committee Hospital la Paz. The accumulated incidence in each group will be calculated, as well as the relative risk (RR) and the number needed to treat (NNT) with their corresponding 95% confidence intervals. We will perform an intention-to-treat analysis by comparing the retrogression from pre-frailty (1 or 2 Fried criteria) to robust status (0 Fried criteria) by the end of the intervention, 6 months and 12 months post-intervention. Secondary variables: sociodemographic, clinical and functional variables exercise program adherence, patient satisfaction with the program and quality of life. Main variable: pre-frailty according to the Fried phenotype. Handing out of at-home exercise chart (twice/week). Exercises for improving aerobic resistance, muscle strength, propioception-balance and flexibility and 3. Multicomponent physical activity program (MEFAP, for its acronym in Spanish) with twelve 1.5 h-weekly sessions comprised of: 1.
#Jackson emc ness trial
Randomized parallel group multicenter clinical trial located in primary care setting, among non-dependent and pre-frail patients > 70 years old, including 190 patients (95 intervention, 95 control group). Our main aim is to evaluate the effect of a multicomponent physical activity program, versus regular medical practice, on reverting pre-frailty status among the elderly, 12 months post-intervention. Physical activity may reverse frailty in the elderly, but we encounter barriers to the implementation of exercise programs in this population. School of Medicine, Autonoma University of Madrid, Madrid, Spain. 17 Preventive Medicine and Public Health Department.15 Family and Community Teaching Unit Norte.14 Research Network in Health Services and Chronic Diseases (REDISSEC), Madrid, Spain.Northern Primary Care Health Directorate of the Community of Madrid, Madrid, Spain. 13 Barrio del Pilar Primary Care Health University Center.12 Fuencarral Primary Care Health University Center.11 Colmenar Viejo Norte Primary Care Health Center.10 Miraflores Primary Care Health Center.9 Torrelaguna Primary Care Health Center.8 Reina Victoria Primary Care Health University Center.7 Valdelasfuentes Primary Care Health Center.6 Health Sciences Department, "Santa Teresa de Jesús" Catholic University of Avila, Avila, Spain.

5 Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain.
